5LSC

The structure of the metallo-beta-lactamase VIM-2 in complex with a triazolylthioacetamide inhibitor

Summary for 5LSC

Entry DOI	10.2210/pdb5lsc/pdb
Descriptor	Metallo-beta-lactamase VIM-2-like protein, CHLORIDE ION, 2-[5-[2-(1,3-benzothiazol-2-ylamino)-2-oxidanylidene-ethyl]sulfanyl-4~{H}-1,2,4-triazol-3-yl]benzoic acid, ... (5 entities in total)
Functional Keywords	antibiotic resistance, carbapenemases, verona integron-encoded metallo-beta-lactamase 2, vim-2, hydrolase
Biological source	Pseudomonas aeruginosa
Total number of polymer chains	2
Total formula weight	52506.73
Authors	Christopeit, T.,Yang, K.-W.,Yang, S.-K.,Leiros, H.-K.S. (deposition date: 2016-08-25, release date: 2016-11-09, Last modification date: 2024-01-17)
Primary citation	Christopeit, T.,Yang, K.W.,Yang, S.K.,Leiros, H.K. The structure of the metallo-beta-lactamase VIM-2 in complex with a triazolylthioacetamide inhibitor. Acta Crystallogr F Struct Biol Commun, 72:813-819, 2016 Cited by PubMed: 27834790 DOI: 10.1107/S2053230X16016113 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.497 Å)

Structure validation