5LRX
Structure of A20 OTU domain bound to ubiquitin
Summary for 5LRX
Entry DOI | 10.2210/pdb5lrx/pdb |
Descriptor | Tumor necrosis factor alpha-induced protein 3, Polyubiquitin-B (3 entities in total) |
Functional Keywords | hydrolase, protease, deubiquitinase, otu domain |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm. A20p50: Cytoplasm: P21580 P21580 Ubiquitin: Cytoplasm : P0CG47 |
Total number of polymer chains | 6 |
Total formula weight | 191241.44 |
Authors | Mevissen, T.E.T.,Kulathu, Y.,Mulder, M.P.C.,Geurink, P.P.,Maslen, S.L.,Gersch, M.,Elliott, P.R.,Burke, J.E.,van Tol, B.D.M.,Akutsu, M.,El Oualid, F.,Kawasaki, M.,Freund, S.M.V.,Ovaa, H.,Komander, D. (deposition date: 2016-08-22, release date: 2016-10-19, Last modification date: 2017-09-13) |
Primary citation | Mevissen, T.E.,Kulathu, Y.,Mulder, M.P.,Geurink, P.P.,Maslen, S.L.,Gersch, M.,Elliott, P.R.,Burke, J.E.,van Tol, B.D.,Akutsu, M.,El Oualid, F.,Kawasaki, M.,Freund, S.M.,Ovaa, H.,Komander, D. Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne. Nature, 538:402-405, 2016 Cited by PubMed: 27732584DOI: 10.1038/nature19836 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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