5LRX

Structure of A20 OTU domain bound to ubiquitin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Tumor necrosis factor alpha-induced protein 3	polymer	371	43514.9	2	UniProt (P21580) Pfam (PF02338) In PDB	Homo sapiens (Human)	TNF alpha-induced protein 3,OTU domain-containing protein 7C,Putative DNA-binding protein A20,Zinc finger protein A20
2	B, D	Polyubiquitin-B	polymer	76	8558.9	2	UniProt (P0CG47) Pfam (PF00240) In PDB	Homo sapiens (Human)
3	E, F	Tumor necrosis factor alpha-induced protein 3	polymer	371	43546.9	2	UniProt (P21580) Pfam (PF02338) In PDB	Homo sapiens (Human)	TNF alpha-induced protein 3,OTU domain-containing protein 7C,Putative DNA-binding protein A20,Zinc finger protein A20

Sequence modifications

A, C: 1 - 366 (UniProt: P21580)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Leu -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

B, D: 1 - 76 (UniProt: P0CG47)

PDB	External Database	Details
Aye 76	Gly 76	engineered mutation

E, F: 1 - 366 (UniProt: P21580)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Leu -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	191241.4
All*	Total formula weight	191241.4

*Water molecules are not included.