5LQK
Crystal Structure of COMT in complex with N-[(E)-3-[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]prop-2-enyl]-2,3-dihydroxy-5-[(4-methylphenyl)methyl]benzamide
Summary for 5LQK
Entry DOI | 10.2210/pdb5lqk/pdb |
Descriptor | Catechol O-methyltransferase, MAGNESIUM ION, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | methyltransferase, neurotransmitter degradation, transferase |
Biological source | Rattus norvegicus (Norway Rat) |
Cellular location | Isoform 2: Cytoplasm. Isoform 1: Cell membrane; Single-pass type II membrane protein; Extracellular side: P22734 |
Total number of polymer chains | 1 |
Total formula weight | 25529.38 |
Authors | Ehler, A.,Lerner, C.,Rudolph, M.G. (deposition date: 2016-08-17, release date: 2016-08-31, Last modification date: 2024-05-01) |
Primary citation | Lerner, C.,Rudolph, M.G. Crystal Structure of COMT To be published, |
Experimental method | X-RAY DIFFRACTION (2.24 Å) |
Structure validation
Download full validation report