5LQK

Crystal Structure of COMT in complex with N-[(E)-3-[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]prop-2-enyl]-2,3-dihydroxy-5-[(4-methylphenyl)methyl]benzamide

Summary for 5LQK

• Entry DOI: 10.2210/pdb5lqk/pdb
• Descriptor: Catechol O-methyltransferase, MAGNESIUM ION, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: methyltransferase, neurotransmitter degradation, transferase
• Biological source: Rattus norvegicus (Norway Rat)
• Cellular location: Isoform 2: Cytoplasm. Isoform 1: Cell membrane; Single-pass type II membrane protein; Extracellular side: P22734
• Total number of polymer chains: 1
• Total formula weight: 25529.38

Authors

Ehler, A.,Lerner, C.,Rudolph, M.G. (deposition date: 2016-08-17, release date: 2016-08-31, Last modification date: 2024-05-01)

• Primary citation: Lerner, C.,Rudolph, M.G.; Crystal Structure of COMT; To be published,

Experimental method

X-RAY DIFFRACTION (2.24 Å)