5LPA

AadA E87Q in complex with ATP, calcium and dihydrostreptomycin

Summary for 5LPA

Entry DOI	10.2210/pdb5lpa/pdb
Descriptor	Streptomycin 3''-adenylyltransferase, ADENOSINE-5'-TRIPHOSPHATE, dihydrostreptomycin, ... (7 entities in total)
Functional Keywords	transferase, aminoglycoside adenyl transferase, ant(3'')9, antibiotic resistance
Biological source	Salmonella enterica subsp. enterica serovar Typhimurium
Total number of polymer chains	2
Total formula weight	63829.28
Authors	Stern, A.L.,Van der Verren, S.E.,Selmer, M. (deposition date: 2016-08-12, release date: 2018-01-17, Last modification date: 2024-01-10)
Primary citation	Stern, A.L.,Van der Verren, S.E.,Kanchugal P, S.,Nasvall, J.,Gutierrez-de-Teran, H.,Selmer, M. Structural mechanism of AadA, a dual-specificity aminoglycoside adenylyltransferase fromSalmonella enterica. J.Biol.Chem., 293:11481-11490, 2018 Cited by PubMed: 29871922 DOI: 10.1074/jbc.RA118.003989 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation