5LJ5
Overall structure of the yeast spliceosome immediately after branching.
Summary for 5LJ5
Entry DOI | 10.2210/pdb5lj5/pdb |
EMDB information | 4057 |
Descriptor | U5 snRNA (small nuclear RNA), Pre-mRNA-splicing factor SNU114, Pre-mRNA-splicing factor ISY1, ... (38 entities in total) |
Functional Keywords | spliceosome, snrnp, pre-mrna splicing, trans-esterification, lariat intermediate, complex c, splicing |
Biological source | Saccharomyces cerevisiae More |
Total number of polymer chains | 45 |
Total formula weight | 2376122.00 |
Authors | Galej, W.P.,Wilkinson, M.F.,Fica, S.M.,Oubridge, C.,Newman, A.J.,Nagai, K. (deposition date: 2016-07-17, release date: 2016-08-31, Last modification date: 2019-12-11) |
Primary citation | Galej, W.P.,Wilkinson, M.E.,Fica, S.M.,Oubridge, C.,Newman, A.J.,Nagai, K. Cryo-EM structure of the spliceosome immediately after branching. Nature, 537:197-201, 2016 Cited by PubMed: 27459055DOI: 10.1038/nature19316 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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