5LGQ
Crystal structure of mouse CARM1 in complex with ligand P2C3s
Summary for 5LGQ
Entry DOI | 10.2210/pdb5lgq/pdb |
Descriptor | Histone-arginine methyltransferase CARM1, Polyadenylate-binding protein 1, 1,2-ETHANEDIOL, ... (9 entities in total) |
Functional Keywords | protein arginine methyltransferase, catalytic domain, chromatin regulator, mrna processing, mrna splicing, nucleus, s-adenosyl-l-methionine, transcription, transcription regulation, transferase |
Biological source | Mus musculus (house mouse) More |
Cellular location | Nucleus: Q9WVG6 Cytoplasm: P11940 |
Total number of polymer chains | 8 |
Total formula weight | 170519.98 |
Authors | Marechal, N.,Troffer-Charlier, N.,Cura, V.,Bonnefond, L.,Cavarelli, J. (deposition date: 2016-07-08, release date: 2017-03-22, Last modification date: 2024-01-10) |
Primary citation | van Haren, M.J.,Marechal, N.,Troffer-Charlier, N.,Cianciulli, A.,Sbardella, G.,Cavarelli, J.,Martin, N.I. Transition state mimics are valuable mechanistic probes for structural studies with the arginine methyltransferase CARM1. Proc. Natl. Acad. Sci. U.S.A., 114:3625-3630, 2017 Cited by PubMed: 28330993DOI: 10.1073/pnas.1618401114 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.11 Å) |
Structure validation
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