5LGK

Crystal structure of the human IgE-Fc bound to its B cell receptor derCD23

Summary for 5LGK

Entry DOI	10.2210/pdb5lgk/pdb
Descriptor	Ig epsilon chain C region, Low affinity immunoglobulin epsilon Fc receptor, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	immunoglobulin fold lectin, antibody receptor, immune system
Biological source	Homo sapiens (Human) More
Cellular location	Secreted : P01854 Cell membrane; Single-pass type II membrane protein: P06734
Total number of polymer chains	6
Total formula weight	166582.34
Authors	Dhaliwal, B.,Pang, M.O.Y.,Sutton, B.J. (deposition date: 2016-07-07, release date: 2017-04-05, Last modification date: 2024-01-10)
Primary citation	Dhaliwal, B.,Pang, M.O.,Keeble, A.H.,James, L.K.,Gould, H.J.,McDonnell, J.M.,Sutton, B.J.,Beavil, A.J. IgE binds asymmetrically to its B cell receptor CD23. Sci Rep, 7:45533-45533, 2017 Cited by PubMed: 28361904 DOI: 10.1038/srep45533 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5 Å)

Structure validation