5LGK
Crystal structure of the human IgE-Fc bound to its B cell receptor derCD23
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Ig epsilon chain C region | polymer | 307 | 34271.4 | 4 | UniProt (P01854) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
| 2 | E, F | Low affinity immunoglobulin epsilon Fc receptor | polymer | 120 | 13940.5 | 2 | UniProt (P06734) Pfam (PF00059) In PDB | Homo sapiens (Human) | BLAST-2,C-type lectin domain family 4 member J,Fc-epsilon-RII,Immunoglobulin E-binding factor,Lymphocyte IgE receptor |
| 3 | G, H | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 4 | A, C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) |
Sequence modifications
A, B, C, D: 234 - 540 (UniProt: P01854)
| PDB | External Database | Details |
|---|---|---|
| - | Leu 133 | deletion |
| Gln 265 | Asn 146 | conflict |
| Gln 371 | Asn 252 | conflict |
| Gln 383 | Asn 264 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 164966.8 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1173.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 166582.3 |
