5LDE

Crystal structure of a vFLIP-IKKgamma stapled peptide dimer

Summary for 5LDE

Entry DOI	10.2210/pdb5lde/pdb
Descriptor	Immunoglobulin G-binding protein G,Viral FLICE protein, Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, isoform CRA_a (2 entities in total)
Functional Keywords	vflip, nf-kb, nemo, viral protein
Biological source	Streptococcus sp. group G More
Total number of polymer chains	4
Total formula weight	65124.43
Authors	Barrett, T. (deposition date: 2016-06-24, release date: 2017-10-04, Last modification date: 2024-01-10)
Primary citation	Briggs, L.C.,Chan, A.W.E.,Davis, C.A.,Whitelock, N.,Hotiana, H.A.,Baratchian, M.,Bagneris, C.,Selwood, D.L.,Collins, M.K.,Barrett, T.E. IKK gamma-Mimetic Peptides Block the Resistance to Apoptosis Associated with Kaposi's Sarcoma-Associated Herpesvirus Infection. J. Virol., 91:-, 2017 Cited by PubMed: 28931678 DOI: 10.1128/JVI.01170-17 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.38 Å)

Structure validation