5L8K
Aurora-A kinase domain in complex with vNAR-D01 (crystal form 2)
Summary for 5L8K
Entry DOI | 10.2210/pdb5l8k/pdb |
Related | 5L8L |
Descriptor | Aurora kinase A, New antigen receptor variable domain, ADENOSINE-5'-DIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | kinase, vnar, inhibitor, transferase |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome : O14965 |
Total number of polymer chains | 2 |
Total formula weight | 46970.84 |
Authors | Burgess, S.G.,Bayliss, R. (deposition date: 2016-06-08, release date: 2016-07-20, Last modification date: 2024-01-10) |
Primary citation | Burgess, S.G.,Oleksy, A.,Cavazza, T.,Richards, M.W.,Vernos, I.,Matthews, D.,Bayliss, R. Allosteric inhibition of Aurora-A kinase by a synthetic vNAR domain. Open Biology, 6:-, 2016 Cited by PubMed: 27411893DOI: 10.1098/rsob.160089 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.79 Å) |
Structure validation
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