5L6Q

Refolded AL protein from cardiac amyloidosis

Summary for 5L6Q

• Entry DOI: 10.2210/pdb5l6q/pdb
• Related: 4OD2
• Descriptor: H5AL, ZINC ION, SODIUM ION, ... (8 entities in total)
• Functional Keywords: antibody, light chain, systemic al amyloidosis, amyloid fibrils, immune system
• Biological source: Homo sapiens
• Total number of polymer chains: 2
• Total formula weight: 25213.06

Authors

Annamalai, K.,Liberta, F.,Vielberg, M.-T.,Lilie, H.,Guehrs, K.-H.,Schierhorn, A.,Koehler, R.,Schmidt, A.,Haupt, C.,Hegenbart, O.,Schoenland, S.,Groll, M.,Faendrich, M. (deposition date: 2016-05-31, release date: 2017-05-31, Last modification date: 2024-01-10)

• Primary citation: Annamalai, K.,Liberta, F.,Vielberg, M.T.,Close, W.,Lilie, H.,Guhrs, K.H.,Schierhorn, A.,Koehler, R.,Schmidt, A.,Haupt, C.,Hegenbart, U.,Schonland, S.,Schmidt, M.,Groll, M.,Fandrich, M.; Common Fibril Structures Imply Systemically Conserved Protein Misfolding Pathways In Vivo.; Angew. Chem. Int. Ed. Engl., 56:7510-7514, 2017; PubMed: 28544119; DOI: 10.1002/anie.201701761

Experimental method

X-RAY DIFFRACTION (1.4 Å)