5L6E

Crystal structure of the human METTL3-METTL14 complex bound to SAM

Summary for 5L6E

• Entry DOI: 10.2210/pdb5l6e/pdb
• Descriptor: N6-adenosine-methyltransferase 70 kDa subunit, N6-adenosine-methyltransferase subunit METTL14, S-ADENOSYLMETHIONINE, ... (6 entities in total)
• Functional Keywords: methyltransferase n6-adenine methylation m6a rossmann fold, transferase
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : Q86U44 Q9HCE5
• Total number of polymer chains: 2
• Total formula weight: 59858.48

Authors

Sledz, P.,Jinek, M. (deposition date: 2016-05-29, release date: 2016-10-12, Last modification date: 2024-01-10)

• Primary citation: Sledz, P.,Jinek, M.; Structural insights into the molecular mechanism of the m(6)A writer complex.; Elife, 5:-, 2016; PubMed: 27627798; DOI: 10.7554/eLife.18434

Experimental method

X-RAY DIFFRACTION (1.901 Å)