5L6E
Crystal structure of the human METTL3-METTL14 complex bound to SAM
Summary for 5L6E
Entry DOI | 10.2210/pdb5l6e/pdb |
Descriptor | N6-adenosine-methyltransferase 70 kDa subunit, N6-adenosine-methyltransferase subunit METTL14, S-ADENOSYLMETHIONINE, ... (6 entities in total) |
Functional Keywords | methyltransferase n6-adenine methylation m6a rossmann fold, transferase |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : Q86U44 Q9HCE5 |
Total number of polymer chains | 2 |
Total formula weight | 59858.48 |
Authors | |
Primary citation | Sledz, P.,Jinek, M. Structural insights into the molecular mechanism of the m(6)A writer complex. Elife, 5:-, 2016 Cited by PubMed: 27627798DOI: 10.7554/eLife.18434 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.901 Å) |
Structure validation
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