5L5A
Yeast 20S proteasome with human beta5i (1-138; R57T)
Summary for 5L5A
Entry DOI | 10.2210/pdb5l5a/pdb |
Related | 5CZ4 |
Descriptor | Proteasome subunit alpha type-2, Proteasome subunit beta type-4, Proteasome subunit beta type-8,Proteasome subunit beta type-5, ... (17 entities in total) |
Functional Keywords | hydrolase complex, proteasome, mutant, binding analysis, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Saccharomyces cerevisiae S288c (Baker's yeast) More |
Total number of polymer chains | 28 |
Total formula weight | 731326.78 |
Authors | Groll, M.,Huber, E.M. (deposition date: 2016-05-28, release date: 2016-11-09, Last modification date: 2024-01-10) |
Primary citation | Huber, E.M.,Heinemeyer, W.,de Bruin, G.,Overkleeft, H.S.,Groll, M. A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit beta 5i. EMBO J., 35:2602-2613, 2016 Cited by PubMed: 27789522DOI: 10.15252/embj.201695222 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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