5L3J
ESCHERICHIA COLI DNA GYRASE B IN COMPLEX WITH BENZOTHIAZOLE-BASED INHIBITOR
Summary for 5L3J
Entry DOI | 10.2210/pdb5l3j/pdb |
Descriptor | DNA gyrase subunit B, 2-[[2-[[4,5-bis(bromanyl)-1~{H}-pyrrol-2-yl]carbonylamino]-1,3-benzothiazol-6-yl]amino]-2-oxidanylidene-ethanoic acid, IODIDE ION, ... (4 entities in total) |
Functional Keywords | gyrase b, inhibitor, complex, gyrb, proteros biostructures, isomerase, proteros biostructures gmbh |
Biological source | Escherichia coli |
Cellular location | Cytoplasm : P0AES6 |
Total number of polymer chains | 1 |
Total formula weight | 42362.03 |
Authors | Gjorgjieva, M.,Tomasic, T.,Barancokova, M.,Katsamakas, S.,Ilas, J.,Montalvao, S.,Tammella, P.,Peterlin Masic, L.,Kikelj, D. (deposition date: 2016-05-23, release date: 2016-08-31, Last modification date: 2024-05-08) |
Primary citation | Gjorgjieva, M.,Tomasic, T.,Barancokova, M.,Katsamakas, S.,Ilas, J.,Tammela, P.,Peterlin Masic, L.,Kikelj, D. Discovery of Benzothiazole Scaffold-Based DNA Gyrase B Inhibitors. J.Med.Chem., 59:8941-8954, 2016 Cited by PubMed: 27541007DOI: 10.1021/acs.jmedchem.6b00864 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.83 Å) |
Structure validation
Download full validation report