5L3J

ESCHERICHIA COLI DNA GYRASE B IN COMPLEX WITH BENZOTHIAZOLE-BASED INHIBITOR

Summary for 5L3J

Entry DOI	10.2210/pdb5l3j/pdb
Descriptor	DNA gyrase subunit B, 2-[[2-[[4,5-bis(bromanyl)-1~{H}-pyrrol-2-yl]carbonylamino]-1,3-benzothiazol-6-yl]amino]-2-oxidanylidene-ethanoic acid, IODIDE ION, ... (4 entities in total)
Functional Keywords	gyrase b, inhibitor, complex, gyrb, proteros biostructures, isomerase, proteros biostructures gmbh
Biological source	Escherichia coli
Cellular location	Cytoplasm : P0AES6
Total number of polymer chains	1
Total formula weight	42362.03
Authors	Gjorgjieva, M.,Tomasic, T.,Barancokova, M.,Katsamakas, S.,Ilas, J.,Montalvao, S.,Tammella, P.,Peterlin Masic, L.,Kikelj, D. (deposition date: 2016-05-23, release date: 2016-08-31, Last modification date: 2016-10-26)
Primary citation	Gjorgjieva, M.,Tomasic, T.,Barancokova, M.,Katsamakas, S.,Ilas, J.,Tammela, P.,Peterlin Masic, L.,Kikelj, D. Discovery of Benzothiazole Scaffold-Based DNA Gyrase B Inhibitors. J.Med.Chem., 59:8941-8954, 2016 Cited by PubMed: 27541007 DOI: 10.1021/acs.jmedchem.6b00864 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.83 Å)

Structure validation