5L2O
Crystal Structure of ALDH1A1 in complex with BUC22
Summary for 5L2O
| Entry DOI | 10.2210/pdb5l2o/pdb |
| Related | 5L13 5L2M 5L2N |
| Descriptor | Retinal dehydrogenase 1, 7-(diethylamino)-4-methyl-2H-1-benzopyran-2-one, YTTERBIUM (III) ION, ... (5 entities in total) |
| Functional Keywords | aldh1a1 inhibitor, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 8 |
| Total formula weight | 442915.20 |
| Authors | Buchman, C.D.,Hurley, T.D. (deposition date: 2016-08-02, release date: 2017-03-08, Last modification date: 2024-03-06) |
| Primary citation | Buchman, C.D.,Hurley, T.D. Inhibition of the Aldehyde Dehydrogenase 1/2 Family by Psoralen and Coumarin Derivatives. J. Med. Chem., 60:2439-2455, 2017 Cited by PubMed: 28219011DOI: 10.1021/acs.jmedchem.6b01825 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
Download full validation report
