5L2H

Crystal Structure of W26A mutant of anti-EGFR Centyrin P54AR4-83v2

Summary for 5L2H

• Entry DOI: 10.2210/pdb5l2h/pdb
• Descriptor: Centyrin, GLYCEROL (3 entities in total)
• Functional Keywords: scaffold protein, fibronectin type iii, beta sandwich, de novo protein
• Biological source: synthetic construct
• Total number of polymer chains: 4
• Total formula weight: 46067.21

Authors

Cardoso, R.M.F.,Goldberg, S.D.,O Neil, K.T.,Gilliland, G.L. (deposition date: 2016-08-01, release date: 2016-11-02, Last modification date: 2024-03-06)

• Primary citation: Goldberg, S.D.,Cardoso, R.M.,Lin, T.,Spinka-Doms, T.,Klein, D.,Jacobs, S.A.,Dudkin, V.,Gilliland, G.,O'Neil, K.T.; Engineering a targeted delivery platform using Centyrins.; Protein Eng. Des. Sel., 29:563-572, 2016; PubMed: 27737926; DOI: 10.1093/protein/gzw054

Experimental method

X-RAY DIFFRACTION (1.8013 Å)