5L1K
PostInsertion complex of Human DNA Polymerase Eta bypassing an O6-Methyl-2'-deoxyguanosine : dC site
Summary for 5L1K
Entry DOI | 10.2210/pdb5l1k/pdb |
Related | 5L1I 5L1J 5L1L |
Descriptor | DNA polymerase eta, DNA (5'-D(*CP*AP*TP*GP*(6OG)P*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*C)-3'), ... (7 entities in total) |
Functional Keywords | catalytic domain, dna damage, dna polymerase, lesion bypass, o6-methyl-2'-deoxyguanosine, y-family polymerase, translesion dna synthesis (tls), dna binding protein., transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : Q9Y253 |
Total number of polymer chains | 3 |
Total formula weight | 55328.62 |
Authors | |
Primary citation | Patra, A.,Zhang, Q.,Guengerich, F.P.,Egli, M. Mechanisms of Insertion of dCTP and dTTP Opposite the DNA Lesion O6-Methyl-2'-deoxyguanosine by Human DNA Polymerase eta. J.Biol.Chem., 291:24304-24313, 2016 Cited by PubMed: 27694439DOI: 10.1074/jbc.M116.755462 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.82 Å) |
Structure validation
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