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5L1K

PostInsertion complex of Human DNA Polymerase Eta bypassing an O6-Methyl-2'-deoxyguanosine : dC site

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase etapolymer43548617.71UniProt (Q9Y253)
Pfam (PF00817)
Pfam (PF21704)
Pfam (PF11799)
Homo sapiens (Human)RAD30 homolog A,Xeroderma pigmentosum variant type protein
2B
(T)
DNA (5'-D(*CP*AP*TP*GP*(6OG)P*TP*GP*AP*CP*GP*CP*T)-3')polymer123692.41SYNTHETIC CONSTRUCT
3C
(P)
DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*C)-3')polymer82411.61SYNTHETIC CONSTRUCT
4D
(A)
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidinenon-polymer466.21Chemie (0KX)
5E, F
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
6G
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
7H, I, J
(A, T, P)
waterwater18.0491Chemie (HOH)
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight54721.7
Non-Polymers*Number of molecules4
Total formula weight606.9
All*Total formula weight55328.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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