5L12

Crystal structure of 2C-methyl-D-erythritol 2,4-clycodiphosphate synthase from BURKHOLDERIA PSEUDOMALLEI double mutant

Summary for 5L12

• Entry DOI: 10.2210/pdb5l12/pdb
• Related: 5L03
• Descriptor: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION (3 entities in total)
• Functional Keywords: mep pathway, ispf, site-directed mutagenesis, doulble mutant, lyase
• Biological source: Burkholderia pseudomallei (strain 1106a)
• Total number of polymer chains: 3
• Total formula weight: 50767.84

Authors

Blain, J.M.,Raneiri, G.,Walter, R.L.,Hagen, T.J.,Horn, J.R. (deposition date: 2016-07-28, release date: 2017-11-01, Last modification date: 2024-03-06)

• Primary citation: Blain, J.M.,Raneiri, G.,Walter, R.L.,Hagen, T.J.,Horn, J.R.; Enzyme Engineering for the Development of a High-Throughput Temperature Screen of Burkholderia pseudomallei IspF Inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.716 Å)