5L11

Human Liver Receptor Homologue-1 (LRH-1) Bound to RJW100 and a Fragment of TIF-2

5L11 の概要

• エントリーDOI: 10.2210/pdb5l11/pdb
• 分子名称: Nuclear receptor subfamily 5 group A member 2, Tif2, (1R,3aR,6aR)-5-hexyl-4-phenyl-3a-(1-phenylethenyl)-1,2,3,3a,6,6a-hexahydropentalen-1-ol, ... (4 entities in total)
• 機能のキーワード: nuclear receptor, agonist, transcription-inhibitor complex, transcription/inhibitor
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 30426.19

構造登録者

Mays, S.G.,Ortlund, E.A. (登録日: 2016-07-28, 公開日: 2016-10-12, 最終更新日: 2023-10-04)

• 主引用文献: Mays, S.G.,Okafor, C.D.,Whitby, R.J.,Goswami, D.,Stec, J.,Flynn, A.R.,Dugan, M.C.,Jui, N.T.,Griffin, P.R.,Ortlund, E.A.; Crystal Structures of the Nuclear Receptor, Liver Receptor Homolog 1, Bound to Synthetic Agonists.; J. Biol. Chem., 291:25281-25291, 2016; PubMed: 27694446; DOI: 10.1074/jbc.M116.753541

実験手法

X-RAY DIFFRACTION (1.849 Å)