5KV9

Crystal structure of a hPIV haemagglutinin-neuraminidase-inhibitor complex

5KV9 の概要

• エントリーDOI: 10.2210/pdb5kv9/pdb
• 関連するPDBエントリー: 4XJQ 4XJR 5KV8
• 分子名称: Hemagglutinin-neuraminidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (7 entities in total)
• 機能のキーワード: haemagglutinin-neuraminidase, hyrdrolase, viral protein, host cell surface receptor binding, hydrolase-inhibitor complex, hydrolase/inhibitor
• 由来する生物種: Human parainfluenza virus 3
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 50386.00

構造登録者

Dirr, L.,El-Deeb, I.M.,Chavas, L.M.G.,Guillon, P.,von Itzstein, M. (登録日: 2016-07-13, 公開日: 2017-07-12, 最終更新日: 2023-10-04)

• 主引用文献: Dirr, L.,El-Deeb, I.M.,Chavas, L.M.G.,Guillon, P.,Itzstein, M.V.; The impact of the butterfly effect on human parainfluenza virus haemagglutinin-neuraminidase inhibitor design.; Sci Rep, 7:4507-4507, 2017; PubMed: 28674426; DOI: 10.1038/s41598-017-04656-y

実験手法

X-RAY DIFFRACTION (2 Å)