5KTP
Crystal structure of Pyrococcus horikoshii quinolinate synthase (NadA) with bound itaconate and Fe4S4 cluster
Summary for 5KTP
| Entry DOI | 10.2210/pdb5ktp/pdb |
| Related | 5KTM 5KTN 5KTO 5KTR 5KTS 5KTT |
| Descriptor | Quinolinate synthase A, IRON/SULFUR CLUSTER, CHLORIDE ION, ... (6 entities in total) |
| Functional Keywords | dehydratase, iron-sulfur cluster, substrate analog complex, biosynthetic enzyme, transferase |
| Biological source | Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) |
| Total number of polymer chains | 1 |
| Total formula weight | 35117.66 |
| Authors | Fenwick, M.K.,Ealick, S.E. (deposition date: 2016-07-12, release date: 2016-07-27, Last modification date: 2023-10-04) |
| Primary citation | Fenwick, M.K.,Ealick, S.E. Crystal Structures of the Iron-Sulfur Cluster-Dependent Quinolinate Synthase in Complex with Dihydroxyacetone Phosphate, Iminoaspartate Analogues, and Quinolinate. Biochemistry, 55:4135-4139, 2016 Cited by PubMed: 27404889DOI: 10.1021/acs.biochem.6b00626 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.542 Å) |
Structure validation
Download full validation report
