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5KR5

Directed Evolution of Transaminases By Ancestral Reconstruction. Using Old Proteins for New Chemistries

Summary for 5KR5
Entry DOI10.2210/pdb5kr5/pdb
Related5KQT 5KQU 5KQW 5KR3 5KR4 5KR6
Descriptor4-aminobutyrate transaminase, PYRIDOXAL-5'-PHOSPHATE, CALCIUM ION, ... (5 entities in total)
Functional Keywordsphylogenetics, directed evolution, transaminase, protein engineering, transferase
Biological sourcePseudomonas
Total number of polymer chains2
Total formula weight105000.67
Authors
Wilding, M.,Newman, J.,Peat, T.S.,Scott, C. (deposition date: 2016-07-07, release date: 2017-07-12, Last modification date: 2023-10-04)
Primary citationWilding, M.,Peat, T.S.,Kalyaanamoorthy, S.,Newman, J.,Scott, C.,Jermiin, L.S.
Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction
Green Chemistry, 19:5375-, 2017
Cited by
DOI: 10.1039/c7gc02343j
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

227561

数据于2024-11-20公开中

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