5KQT

Directed Evolution of Transaminases By Ancestral Reconstruction. Using Old Proteins for New Chemistries

5KQT の概要

• エントリーDOI: 10.2210/pdb5kqt/pdb
• 関連するPDBエントリー: 5KQU 5KQW 5KR3 5KR4 5KR5 5KR6
• 分子名称: 4-aminoburyrate transaminase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE, ... (6 entities in total)
• 機能のキーワード: phylogenetics, directed evolution, transaminase, protein engineering, transferase
• 由来する生物種: Pseudomonas sp. AAC
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 52028.35

構造登録者

Wilding, M.,Newman, J.,Peat, T.S.,Scott, C. (登録日: 2016-07-06, 公開日: 2017-07-12, 最終更新日: 2023-10-04)

• 主引用文献: Wilding, M.,Peat, T.S.,Kalyaanamoorthy, S.,Newman, J.,Scott, C.,Jermiin, L.S.; Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction; Green Chemistry, 19:5375-, 2017; DOI: 10.1039/c7gc02343j

実験手法

X-RAY DIFFRACTION (1.99 Å)