5KQM
Co-crystal structure of LMW-PTP in complex with MES
Summary for 5KQM
Entry DOI | 10.2210/pdb5kqm/pdb |
Related | 5KQG 5KQL 5KQP |
Descriptor | Low molecular weight phosphotyrosine protein phosphatase, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID (3 entities in total) |
Functional Keywords | lmw-ptp, inhibitor, complex, hydrolase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: P24666 |
Total number of polymer chains | 1 |
Total formula weight | 20432.12 |
Authors | Wang, J.,Zhang, Z.-Y.,Yu, Z.-H. (deposition date: 2016-07-06, release date: 2016-10-12, Last modification date: 2023-10-04) |
Primary citation | He, R.,Wang, J.,Yu, Z.H.,Zhang, R.Y.,Liu, S.,Wu, L.,Zhang, Z.Y. Inhibition of low molecular weight protein tyrosine phosphatase by an induced-fit mechanism. J.Med.Chem., 2016 Cited by PubMed: 27676368DOI: 10.1021/acs.jmedchem.6b00993 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.91 Å) |
Structure validation
Download full validation report