5KQM

Co-crystal structure of LMW-PTP in complex with MES

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Low molecular weight phosphotyrosine protein phosphatase	polymer	178	20236.9	1	UniProt (P24666) Pfam (PF01451) In PDB	Homo sapiens (Human)	LMW-PTPase,Adipocyte acid phosphatase,Low molecular weight cytosolic acid phosphatase,Red cell acid phosphatase 1
2	A	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	1	Chemie (MES)
3		water	water		18.0	121	Chemie (HOH)

Sequence modifications

A: 0 - 157 (UniProt: P24666)

PDB	External Database	Details
Met -20	-	initiating methionine
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Val -6	-	expression tag
Pro -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	20236.9
Non-Polymers*	Number of molecules	1
	Total formula weight	195.2
All*	Total formula weight	20432.1

*Water molecules are not included.