5KOV

Crystal structure of the human astrovirus 2 capsid protein spike in complex with a single chain variable fragment of an astrovirus neutralizing antibody at 3.24-A resolution

5KOV の概要

• エントリーDOI: 10.2210/pdb5kov/pdb
• 分子名称: Capsid polyprotein VP90, PL-2 scFv chain, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: viral protein, capsid protein, icosahedral virus, single chain variable fragment.
• 由来する生物種: Human astrovirus-2 (HAstV-2); 詳細
• タンパク質・核酸の鎖数: 16
• 化学式量合計: 422557.46

構造登録者

Bogdanoff, W.A.,DuBois, R.M. (登録日: 2016-07-01, 公開日: 2016-11-09, 最終更新日: 2023-10-04)

• 主引用文献: Bogdanoff, W.A.,Campos, J.,Perez, E.I.,Yin, L.,Alexander, D.L.,DuBois, R.M.; Structure of a Human Astrovirus Capsid-Antibody Complex and Mechanistic Insights into Virus Neutralization.; J. Virol., 91:-, 2017; PubMed: 27807234; DOI: 10.1128/JVI.01859-16

実験手法

X-RAY DIFFRACTION (3.245 Å)