5KJ8

Structure of the Ca2+-bound synaptotagmin-1 SNARE complex (long unit cell form) - from synchrotron diffraction

5KJ8 の概要

• エントリーDOI: 10.2210/pdb5kj8/pdb
• 関連するPDBエントリー: 5KJ7
• 分子名称: Vesicle-associated membrane protein 3, Syntaxin-1A, Synaptosomal-associated protein 25, ... (6 entities in total)
• 機能のキーワード: xfel structure, synaptic fusion complex, synaptotagmin1, neuronal snare complex, endocytosis, exocytosis
• 由来する生物種: Rattus norvegicus (Rat); 詳細
• 細胞内の位置: Membrane ; Single-pass type IV membrane protein : P63025; Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass type IV membrane protein : P32851; Cytoplasm, perinuclear region : P60881 P60881; Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass membrane protein : P21707
• タンパク質・核酸の鎖数: 11
• 化学式量合計: 158567.05

構造登録者

Lyubimov, A.Y.,Uervirojnangkoorn, M.,Zhou, Q.,Zhao, M.,Sauter, N.K.,Brewster, A.S.,Weis, W.I.,Brunger, A.T. (登録日: 2016-06-17, 公開日: 2016-10-19, 最終更新日: 2023-09-27)

• 主引用文献: Lyubimov, A.Y.,Uervirojnangkoorn, M.,Zeldin, O.B.,Zhou, Q.,Zhao, M.,Brewster, A.S.,Michels-Clark, T.,Holton, J.M.,Sauter, N.K.,Weis, W.I.,Brunger, A.T.; Advances in X-ray free electron laser (XFEL) diffraction data processing applied to the crystal structure of the synaptotagmin-1 / SNARE complex.; Elife, 5:-, 2016; PubMed: 27731796; DOI: 10.7554/eLife.18740

実験手法

X-RAY DIFFRACTION (4.1 Å)