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5KH2

Crystal Structure of Steptococcus pneumoniae Undecaprenyl pyrophosphate Synthase (UPPS)

Summary for 5KH2
Entry DOI10.2210/pdb5kh2/pdb
Related5KH4 5KH5
DescriptorIsoprenyl transferase (2 entities in total)
Functional Keywordsupps, native, bacterial, undecaprenyl s. pneumoniae, transferase
Biological sourceStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Total number of polymer chains4
Total formula weight123644.82
Authors
Concha, N.O. (deposition date: 2016-06-14, release date: 2016-07-20, Last modification date: 2024-03-06)
Primary citationConcha, N.,Huang, J.,Bai, X.,Benowitz, A.,Brady, P.,Grady, L.C.,Kryn, L.H.,Holmes, D.,Ingraham, K.,Jin, Q.,Pothier Kaushansky, L.,McCloskey, L.,Messer, J.A.,O'Keefe, H.,Patel, A.,Satz, A.L.,Sinnamon, R.H.,Schneck, J.,Skinner, S.R.,Summerfield, J.,Taylor, A.,Taylor, J.D.,Evindar, G.,Stavenger, R.A.
Discovery and Characterization of a Class of Pyrazole Inhibitors of Bacterial Undecaprenyl Pyrophosphate Synthase.
J.Med.Chem., 59:7299-7304, 2016
Cited by
PubMed: 27379833
DOI: 10.1021/acs.jmedchem.6b00746
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

217705

數據於2024-03-27公開中

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