5KGK

Crystal structure of PIM1 with inhibitor: 3-(4-methoxyphenyl)-1~{H}-pyrazol-5-amine

Summary for 5KGK

• Entry DOI: 10.2210/pdb5kgk/pdb
• Related: 5KGD 5KGE 5KGG 5KGI
• Descriptor: Serine/threonine-protein kinase pim-1, 1,2-ETHANEDIOL, 3-(4-methoxyphenyl)-1~{H}-pyrazol-5-amine, ... (5 entities in total)
• Functional Keywords: kinase, transferase, serine/threonine-protein kinase pim-1, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (Human)
• Cellular location: Isoform 2: Cytoplasm. Isoform 1: Cell membrane: P11309
• Total number of polymer chains: 1
• Total formula weight: 32658.95

Authors

Ferguson, A.D. (deposition date: 2016-06-13, release date: 2017-08-09, Last modification date: 2023-09-27)

• Primary citation: Ferguson, A.D.; Structure of PIM1 in complex with inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.66 Å)