5KE4

Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 6 nicotinic acetylcholine receptor in complex with 2-((5-(3,7-Diazabicyclo[3.3.1]nonan-3-yl)pyridin-3-yl)oxy)- N,N-dimethylethanamine (BPC)

Summary for 5KE4

• Entry DOI: 10.2210/pdb5ke4/pdb
• Descriptor: Soluble acetylcholine receptor, 2-((5-(3,7-Diazabicyclo[3.3.1]nonan-3-yl)pyridin-3-yl)oxy)-N,N-dimethylethanamine (3 entities in total)
• Functional Keywords: nicotinic, acetylcholine, achbp, acetylcholine-binding protein
• Biological source: Aplysia californica (California sea hare)
• Total number of polymer chains: 5
• Total formula weight: 132522.49

Authors

Bobango, J.,Wu, J.,Talley, I.T.,Ralston, R.,Sankaran, B.,Talley, T.T. (deposition date: 2016-06-09, release date: 2016-07-06)

• Primary citation: Bobango, J.,Wu, J.,Talley, I.T.,Ralston, R.,Sankaran, B.,Talley, T.T.; Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 6 nicotinic acetylcholine receptor in complex with 2-((5-(3,7-Diazabicyclo[3.3.1]nonan-3-yl)pyridin-3-yl)oxy)- N,N-dimethylethanamine (BPC); To Be Published,

Experimental method

X-RAY DIFFRACTION (2.554 Å)