5KDO

Heterotrimeric complex of the 4 alanine insertion variant of the Gi alpha1 subunit and the Gbeta1-Ggamma1

5KDO の概要

• エントリーDOI: 10.2210/pdb5kdo/pdb
• 関連するPDBエントリー: 5KDL
• 分子名称: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, ... (5 entities in total)
• 機能のキーワード: heterotrimeric g protein g protein coupled receptors g protein activation g protein structure gdp release, signaling protein
• 由来する生物種: Rattus norvegicus (Rat); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 87100.40

構造登録者

Kaya, A.I.,Lokits, A.D.,Gilbert, J.,Iverson, T.M.,Meiler, J.,Hamm, H.E. (登録日: 2016-06-08, 公開日: 2016-08-03, 最終更新日: 2023-09-27)

• 主引用文献: Kaya, A.I.,Lokits, A.D.,Gilbert, J.A.,Iverson, T.M.,Meiler, J.,Hamm, H.E.; A Conserved Hydrophobic Core in G alpha i1 Regulates G Protein Activation and Release from Activated Receptor.; J.Biol.Chem., 291:19674-19686, 2016; PubMed: 27462082; DOI: 10.1074/jbc.M116.745513

実験手法

X-RAY DIFFRACTION (1.9 Å)