5KDI
How FAPP2 Selects Simple Glycosphingolipids Using the GLTP-fold
Summary for 5KDI
Entry DOI | 10.2210/pdb5kdi/pdb |
Descriptor | Pleckstrin homology domain-containing family A member 8, (~{Z})-~{N}-[(~{E},2~{S},3~{R})-1-[(2~{R},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-3-oxidanyl-octadec-4-en-2-yl]octadec-9-enamide (3 entities in total) |
Functional Keywords | gltp-fold, lipid transfer, lipid transport |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 48430.20 |
Authors | Ochoa-Lizarralde, B.,Popov, A.N.,Samygina, V.R.,Patel, D.J.,Brown, R.E.,Malinina, L. (deposition date: 2016-06-08, release date: 2017-12-13, Last modification date: 2023-09-27) |
Primary citation | Ochoa-Lizarralde, B.,Gao, Y.G.,Popov, A.N.,Samygina, V.R.,Zhai, X.,Mishra, S.K.,Boldyrev, I.A.,Molotkovsky, J.G.,Simanshu, D.K.,Patel, D.J.,Brown, R.E.,Malinina, L. Structural analyses of 4-phosphate adaptor protein 2 yield mechanistic insights into sphingolipid recognition by the glycolipid transfer protein family. J.Biol.Chem., 293:16709-16723, 2018 Cited by PubMed: 30206120DOI: 10.1074/jbc.RA117.000733 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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