5KD4
Crystal Structure of Murine MHC-I H-2Dd in complex with Murine Beta2-Microglobulin and a Variant of Peptide (PVI10) of HIV gp120 MN Isolate (IGPGRAFYVI)
Summary for 5KD4
Entry DOI | 10.2210/pdb5kd4/pdb |
Related | 3ECB |
Descriptor | H-2 class I histocompatibility antigen, D-D alpha chain, Beta-2-microglobulin, Peptide of HIV gp120 MN isolate, PVI10 (IGPGRAFYVI) (3 entities in total) |
Functional Keywords | major histompatibility complex class i, mhc-i, h2-dd, h-2dd, hiv peptide, pvi10, glycoprotein, immune response, immune system |
Biological source | Mus musculus (Mouse) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01900 Secreted: P01887 |
Total number of polymer chains | 6 |
Total formula weight | 90301.49 |
Authors | Jiang, J.,Natarajan, K.,Margulies, D. (deposition date: 2016-06-07, release date: 2017-10-11, Last modification date: 2023-09-27) |
Primary citation | Frey, B.F.,Jiang, J.,Sui, Y.,Boyd, L.F.,Yu, B.,Tatsuno, G.,Billeskov, R.,Solaymani-Mohammadi, S.,Berman, P.W.,Margulies, D.H.,Berzofsky, J.A. Effects of Cross-Presentation, Antigen Processing, and Peptide Binding in HIV Evasion of T Cell Immunity. J. Immunol., 200:1853-1864, 2018 Cited by PubMed: 29374075DOI: 10.4049/jimmunol.1701523 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.05 Å) |
Structure validation
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