5KD0

Crystal structure of the aromatic prenyltransferase AtaPT(E91A) mutant from Aspergillus terreus A8-4 in complex with geranyl S-thiolodiphosphate and (+)-butyrolactone II

Summary for 5KD0

Entry DOI	10.2210/pdb5kd0/pdb
Related	5KCG 5KCL 5KCQ 5KCY 5KD6 5KDA
Descriptor	aromatic prenyltransferase, methyl (2~{R})-3-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-4-oxidanyl-5-oxidanylidene-furan-2-carboxylate, GERANYL S-THIOLODIPHOSPHATE, ... (4 entities in total)
Functional Keywords	substrate promiscuity, abba fold, transferase
Biological source	Aspergillus terreus
Total number of polymer chains	2
Total formula weight	94037.52
Authors	Sun, F.,Gao, B. (deposition date: 2016-06-07, release date: 2016-12-21, Last modification date: 2023-11-08)
Primary citation	Chen, R.,Gao, B.,Liu, X.,Ruan, F.,Zhang, Y.,Lou, J.,Feng, K.,Wunsch, C.,Li, S.M.,Dai, J.,Sun, F. Molecular insights into the enzyme promiscuity of an aromatic prenyltransferase. Nat. Chem. Biol., 13:226-234, 2017 Cited by PubMed: 27992881 DOI: 10.1038/nchembio.2263 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.82 Å)

Structure validation