5KCY

Crystal structure of the aromatic prenyltransferase AtaPT from Aspergillus terreus A8-4 in complex with geranyl S-thiolodiphosphate and (+)-butyrolactone II

Summary for 5KCY

• Entry DOI: 10.2210/pdb5kcy/pdb
• Related: 5KCG 5KCL 5KCQ 5KD0 5KD6 5KDA
• Descriptor: aromatic prenyltransferase, methyl (2~{R})-3-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-4-oxidanyl-5-oxidanylidene-furan-2-carboxylate, GERANYL S-THIOLODIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: substrate promiscuity, abba fold, transferase
• Biological source: Aspergillus terreus
• Total number of polymer chains: 2
• Total formula weight: 95164.74

Authors

Sun, F.,Gao, B. (deposition date: 2016-06-07, release date: 2016-12-21, Last modification date: 2024-03-20)

• Primary citation: Chen, R.,Gao, B.,Liu, X.,Ruan, F.,Zhang, Y.,Lou, J.,Feng, K.,Wunsch, C.,Li, S.M.,Dai, J.,Sun, F.; Molecular insights into the enzyme promiscuity of an aromatic prenyltransferase.; Nat. Chem. Biol., 13:226-234, 2017; PubMed: 27992881; DOI: 10.1038/nchembio.2263

Experimental method

X-RAY DIFFRACTION (2.3 Å)