5K8P

Zn2+/Tetrahedral intermediate-bound R289A 5-nitroanthranilate aminohydrolase

Summary for 5K8P

• Entry DOI: 10.2210/pdb5k8p/pdb
• Related: 5K8M 5K8N 5K8O
• Descriptor: 5-nitroanthranilic acid aminohydrolase, ZINC ION, (6~{R})-6-azanyl-3-nitro-6-oxidanyl-cyclohexa-1,3-diene-1-carboxylic acid, ... (5 entities in total)
• Functional Keywords: nitroaromatics, deaminase, metalloenzyme, hydrolase
• Biological source: Bradyrhizobium sp.
• Total number of polymer chains: 8
• Total formula weight: 372976.42

Authors

Kalyoncu, S. (deposition date: 2016-05-30, release date: 2016-10-05, Last modification date: 2023-09-27)

• Primary citation: Kalyoncu, S.,Heaner, D.P.,Kurt, Z.,Bethel, C.M.,Ukachukwu, C.U.,Chakravarthy, S.,Spain, J.C.,Lieberman, R.L.; Enzymatic hydrolysis by transition-metal-dependent nucleophilic aromatic substitution.; Nat.Chem.Biol., 12:1031-1036, 2016; PubMed: 27694799; DOI: 10.1038/nchembio.2191

Experimental method

X-RAY DIFFRACTION (2.2 Å)