5K5C

Structure of Mycobacterium thermoresistibile trehalose-6-phosphate synthase in a complex with Trehalose.

Summary for 5K5C

• Entry DOI: 10.2210/pdb5k5c/pdb
• Related PRD ID: PRD_900006
• Descriptor: Alpha,alpha-trehalose-phosphate synthase, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ... (5 entities in total)
• Functional Keywords: otsa trehalose-6-phosphate synthase, trehalose, transferase
• Biological source: Mycobacterium thermoresistibile
• Total number of polymer chains: 1
• Total formula weight: 55934.47

Authors

Mendes, V.,Verma, N.,Blaszczyk, M.,Blundell, T.L. (deposition date: 2016-05-23, release date: 2017-06-07, Last modification date: 2024-01-10)

• Primary citation: Mendes, V.,Acebron-Garcia-de-Eulate, M.,Verma, N.,Blaszczyk, M.,Dias, M.V.B.,Blundell, T.L.; Mycobacterial OtsA Structures Unveil Substrate Preference Mechanism and Allosteric Regulation by 2-Oxoglutarate and 2-Phosphoglycerate.; Mbio, 10:-, 2019; PubMed: 31772052; DOI: 10.1128/mBio.02272-19

Experimental method

X-RAY DIFFRACTION (1.848 Å)