5K3L

Crystal structure of Retinoic acid receptor-related orphan receptor (ROR) gamma ligand binding domain complex with 444

Summary for 5K3L

• Entry DOI: 10.2210/pdb5k3l/pdb
• Related: 5K38 5K3M 5K3N
• Descriptor: Nuclear receptor ROR-gamma, N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE (3 entities in total)
• Functional Keywords: double helix, protein binding
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : P51449
• Total number of polymer chains: 4
• Total formula weight: 116810.49

Authors

Huang, P.,Rastinejad, F. (deposition date: 2016-05-19, release date: 2017-05-31, Last modification date: 2024-03-06)

• Primary citation: Lu, J.,Rastinejad, F.; Crystal structure of Retinoic acid receptor-related orphan receptor (ROR) gamma ligand binding domain complex with 444; To be published,

Experimental method

X-RAY DIFFRACTION (2.75 Å)