5K22

Crystal structure of the complex between human PRL-2 phosphatase in reduced state and Bateman domain of human CNNM3

Summary for 5K22

• Entry DOI: 10.2210/pdb5k22/pdb
• Related: 5K23 5K24 5K25
• Descriptor: Protein tyrosine phosphatase type IVA 2, Metal transporter CNNM3 (3 entities in total)
• Functional Keywords: alpha-beta fold, complex, protein binding, phosphatase, transport protein-protein binding complex, transport protein/protein binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 38430.89

Authors

Kozlov, G.,Wu, H.,Gehring, K. (deposition date: 2016-05-18, release date: 2016-10-12, Last modification date: 2024-03-06)

• Primary citation: Gulerez, I.,Funato, Y.,Wu, H.,Yang, M.,Kozlov, G.,Miki, H.,Gehring, K.; Phosphocysteine in the PRL-CNNM pathway mediates magnesium homeostasis.; EMBO Rep., 17:1890-1900, 2016; PubMed: 27856537; DOI: 10.15252/embr.201643393

Experimental method

X-RAY DIFFRACTION (3 Å)