5K0E

Crystal Structure of COMT in complex with 2,4-dimethyl-5-[3-(2-phenylpropan-2-yl)-1H-pyrazol-5-yl]-1,3-thiazole

Summary for 5K0E

• Entry DOI: 10.2210/pdb5k0e/pdb
• Descriptor: Catechol O-methyltransferase, SODIUM ION, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ... (6 entities in total)
• Functional Keywords: methyltransferase, neurotransmitter degradation, catechol, transferase
• Biological source: Rattus norvegicus (Norway Rat)
• Total number of polymer chains: 1
• Total formula weight: 24610.68

Authors

Ehler, A.,Rodriguez-Sarmiento, R.M.,Rudolph, M.G. (deposition date: 2016-05-17, release date: 2016-09-07, Last modification date: 2019-06-12)

• Primary citation: Ehler, A.,Rodriguez-Sarmiento, R.M.,Rudolph, M.G.; Crystal Structure of COMT; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)