5JZN
Crystal structure of DCLK1-KD in complex with NVP-TAE684
Summary for 5JZN
Entry DOI | 10.2210/pdb5jzn/pdb |
Related | 5JZJ |
Descriptor | Serine/threonine-protein kinase DCLK1, 5-CHLORO-N-[2-METHOXY-4-[4-(4-METHYLPIPERAZIN-1-YL)PIPERIDIN-1-YL]PHENYL]-N'-(2-PROPAN-2-YLSULFONYLPHENYL)PYRIMIDINE-2,4-DIAMINE, SULFATE ION, ... (4 entities in total) |
Functional Keywords | kinase, doublecortin, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 63923.96 |
Authors | |
Primary citation | Patel, O.,Dai, W.,Mentzel, M.,Griffin, M.D.,Serindoux, J.,Gay, Y.,Fischer, S.,Sterle, S.,Kropp, A.,Burns, C.J.,Ernst, M.,Buchert, M.,Lucet, I.S. Biochemical and Structural Insights into Doublecortin-like Kinase Domain 1. Structure, 24:1550-1561, 2016 Cited by PubMed: 27545623DOI: 10.1016/j.str.2016.07.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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