5JXI
Structure of the unliganded form of the proprotein convertase furin in presence of EDTA.
Summary for 5JXI
Entry DOI | 10.2210/pdb5jxi/pdb |
Descriptor | Furin, CALCIUM ION, SODIUM ION, ... (5 entities in total) |
Functional Keywords | protease, apo-structure, proteolysis, hydrolase |
Biological source | Homo sapiens (Human) |
Cellular location | Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein: P09958 |
Total number of polymer chains | 1 |
Total formula weight | 52625.06 |
Authors | Dahms, S.O.,Arciniega, M.,Steinmetzer, T.,Huber, R.,Than, M.E. (deposition date: 2016-05-13, release date: 2016-10-05, Last modification date: 2024-01-10) |
Primary citation | Dahms, S.O.,Arciniega, M.,Steinmetzer, T.,Huber, R.,Than, M.E. Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism. Proc.Natl.Acad.Sci.USA, 113:11196-11201, 2016 Cited by PubMed: 27647913DOI: 10.1073/pnas.1613630113 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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