5JVY
Crystal structure of S121P murine COX-2 mutant
Summary for 5JVY
Entry DOI | 10.2210/pdb5jvy/pdb |
Related | 5JVZ 5JW1 |
Descriptor | Prostaglandin G/H synthase 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
Functional Keywords | cyclooxygenase, cox, nsaid, oxidoreductase |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 2 |
Total formula weight | 130396.11 |
Authors | Orlando, B.J.,Malkowski, M.G.,Dong, L. (deposition date: 2016-05-11, release date: 2016-10-26, Last modification date: 2023-09-27) |
Primary citation | Dong, L.,Yuan, C.,Orlando, B.J.,Malkowski, M.G.,Smith, W.L. Fatty Acid Binding to the Allosteric Subunit of Cyclooxygenase-2 Relieves a Tonic Inhibition of the Catalytic Subunit. J.Biol.Chem., 291:25641-25655, 2016 Cited by PubMed: 27756840DOI: 10.1074/jbc.M116.757310 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.36 Å) |
Structure validation
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