5JVG

The large ribosomal subunit from Deinococcus radiodurans in complex with avilamycin

5JVG の概要

• エントリーDOI: 10.2210/pdb5jvg/pdb
• 分子名称: 23S ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (33 entities in total)
• 機能のキーワード: deinococcus radiodurans, avilamycin, degradable antibiotics, ribosome, large ribosomal subunit, resistance
• 由来する生物種: Deinococcus radiodurans R1; 詳細
• タンパク質・核酸の鎖数: 29
• 化学式量合計: 1372760.85

構造登録者

Krupkin, M.,Wekselman, I.,Matzov, D.,Eyal, Z.,Diskin Posner, Y.,Rozenberg, H.,Zimmerman, E.,Bashan, A.,Yonath, A. (登録日: 2016-05-11, 公開日: 2016-11-09, 最終更新日: 2024-01-10)

• 主引用文献: Krupkin, M.,Wekselman, I.,Matzov, D.,Eyal, Z.,Diskin Posner, Y.,Rozenberg, H.,Zimmerman, E.,Bashan, A.,Yonath, A.; Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding.; Proc.Natl.Acad.Sci.USA, 113:E6796-E6805, 2016; PubMed: 27791159; DOI: 10.1073/pnas.1614297113

実験手法

X-RAY DIFFRACTION (3.428 Å)