5JT6

tRNA guanine Transglycosylase (TGT) in co-crystallized complex with 2-((2-morpholinoethyl)amino)-1H-benzo[d]imidazole-5-carbohydrazide

5JT6 の概要

• エントリーDOI: 10.2210/pdb5jt6/pdb
• 関連するPDBエントリー: 1P0D 3S1G 4KWO 4PUK 5I07 5J9M 5J9N 5J9O 5JT5
• 分子名称: Queuine tRNA-ribosyltransferase, ZINC ION, GLYCEROL, ... (6 entities in total)
• 機能のキーワード: benzimidazole-derivatives, shigellosis, transferase, transferase inhibitor
• 由来する生物種: Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43515.10

構造登録者

Ehrmann, F.R.,Heine, A.,Klebe, G. (登録日: 2016-05-09, 公開日: 2017-05-24, 最終更新日: 2024-01-10)

• 主引用文献: Ehrmann, F.R.,Hohn, C.,Heine, A.,Diederich, F.,Klebe, G.; Benzimidazole-based Inhibitors as a Novel Scaffold to Inhibit Z.mobilis TGT and Study Protein Flexibility and the Contributions of Active Site Residues to Binding Affinity of lin-Benzopurines.; To be Published,

実験手法

X-RAY DIFFRACTION (1.54 Å)