5JS2
Human Argonaute-2 Bound to a Modified siRNA
Summary for 5JS2
Entry DOI | 10.2210/pdb5js2/pdb |
Related | 5JS1 |
Descriptor | Protein argonaute-2, modified siRNA, PHENOL, ... (6 entities in total) |
Functional Keywords | argonaute, sirna, rnai, nuclease, hydrolase-rna complex, hydrolase/rna |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm, P-body: Q9UKV8 |
Total number of polymer chains | 2 |
Total formula weight | 99650.11 |
Authors | Schirle, N.T.,MacRae, I.J. (deposition date: 2016-05-07, release date: 2016-07-20, Last modification date: 2023-09-27) |
Primary citation | Schirle, N.T.,Kinberger, G.A.,Murray, H.F.,Lima, W.F.,Prakash, T.P.,MacRae, I.J. Structural Analysis of Human Argonaute-2 Bound to a Modified siRNA Guide. J.Am.Chem.Soc., 138:8694-8697, 2016 Cited by PubMed: 27380263DOI: 10.1021/jacs.6b04454 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.954 Å) |
Structure validation
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