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5JR2

Crystal structure of the EphA4 LBD in complex with APYd3 peptide inhibitor

Summary for 5JR2
Entry DOI10.2210/pdb5jr2/pdb
DescriptorEphrin type-A receptor 4, APYd3 peptide, HEXANE-1,6-DIOL, ... (5 entities in total)
Functional Keywordsreceptor tyrosine kinase, peptide inhibitor, ephrin, als, transferase-inhibitor complex, transferase/inhibitor
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains8
Total formula weight89020.84
Authors
Lechtenberg, B.C.,Olson, E.J.,Pasquale, E.B.,Dawson, P.E.,Riedl, S.J. (deposition date: 2016-05-05, release date: 2016-07-06, Last modification date: 2023-09-27)
Primary citationOlson, E.J.,Lechtenberg, B.C.,Zhao, C.,Rubio de la Torre, E.,Lamberto, I.,Riedl, S.J.,Dawson, P.E.,Pasquale, E.B.
Modifications of a Nanomolar Cyclic Peptide Antagonist for the EphA4 Receptor To Achieve High Plasma Stability.
Acs Med.Chem.Lett., 7:841-846, 2016
Cited by
PubMed: 27660688
DOI: 10.1021/acsmedchemlett.6b00132
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.75 Å)
Structure validation

217705

건을2024-03-27부터공개중

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