5JMY

NEPRILYSIN COMPLEXED WITH LBQ657

Summary for 5JMY

• Entry DOI: 10.2210/pdb5jmy/pdb
• Descriptor: Neprilysin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: hydrolase, lbq657, sacubitril, heart failure
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 162585.10

Authors

Schiering, N.,Wiesmann, C. (deposition date: 2016-04-29, release date: 2016-06-15, Last modification date: 2024-01-10)

• Primary citation: Schiering, N.,D'Arcy, A.,Villard, F.,Ramage, P.,Logel, C.,Cumin, F.,Ksander, G.M.,Wiesmann, C.,Karki, R.G.,Mogi, M.; Structure of neprilysin in complex with the active metabolite of sacubitril.; Sci Rep, 6:27909-27909, 2016; PubMed: 27302413; DOI: 10.1038/srep27909

Experimental method

X-RAY DIFFRACTION (2 Å)